The 24 elders (4:4) are probably representative of the twelve tribes of Israel and the twelve apostles. The white robes and golden crowns signifying righteousness.
In heaven God is exalted (4:5-11). It has also been said after a reading of this book that it seems that heaven is a noisy place!
The lamb “as if slain” in 4:6 is Christ. Seven is a number of perfection, completeness. Horns represent power and eyes represent the knowledge that comes from seeing.
With slight variation the foursome of tribe, tongue, people, and nation occurs seven times within this book (5:9; 7:9; 10:11; 11:9; 13:7; 14:6; 17:15). The word order isn’t always the same. The word tribe is missing from 10:11 and 17:15. In the former we find the word kings substituted, and in the latter the word multitudes. Also in four cases the words are in the singular and in four they are in the plural. In Revelation four seems to represent the earth (four corners, four winds, etc.) and these four groups seem to represent not ALL of humanity, but all “who dwell upon the earth,” that is those opposed to God. He takes His people from out of these groups–they are no longer a part of the groups. This is also a reminder that God’s people are composed of all these groups, not merely one or two!
The word myriad (5:11) means ten thousand, so it’s plural would mean tens of thousands.
Notice in 5:12 that the number of those things which the Lamb is worthy to receive is seven.
The commands to “Come!” in chapter six could also be translated as “Go!” The dead of 6:9-11 are those who were martyred for their faith during that first generation of Christianity.
The number 144,000 (7:4-8), as are most numbers in Revelation, is purely representative. That is to say that one should not look for exactly 144,000 souls. First of all the number is derived from the square of twelve, a number representative of the tribes of Israel and of the Apostles of Christ. This is then multiplies against the cube of ten, our base number. The Greeks and the Hebrews did not have a separate systems of numerals as do we. They used instead their alphabets. Therefore every word had a numerical value. Numerology (the study of numbers) was therefore much more common in their day. They were more conscious of the “value” of a word. For whatever reason, the tribe of Dan is missing from this list of twelve tribes–Manasseh is mentioned instead. If you were to write down the order the names of the sons appear in Genesis 35:23-26 and then write a number for where they appear in this list that numbering would be 2, 7, 8, 1, 9, 10, 11, 12, missing, 5, 3, 4, and Manasseh is added at 6.
Seven appellations of that which is due to God between the two Amens in 7:12 also.
Silence in heaven for half an hour after all that John has recorded thus far would be remarkable and significant (8:1).
There is a third of various things destroyed after the trumpet blasts of chapter 8. Is this a retelling of the seven seals in somewhat of an intensification and less detail?
Proverbs: Be very careful of those who only want you to give and to those things which never say “enough.” Learn from these other groupings as well.